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Introduction: Increased cell growth forming a clone of cells resulting in a malignant, invasive and rather fast growing tumour with the capability of migration and metastasis is called cancer. Cancer has a high incidence rate with one in 4 deaths due to cancer in the USA. CAM therapies are popular among cancer patients and have especially been known to go alongside medical treatment as a support for treating the side effects of conventional treatment, pain control and emotional issues. Historically, there is a long tradition of treating cancer homeopathically. The aim of this study is to consider if there is evidence of current effectiveness of homeopathic treatment of malignant tumours in humans.Method: A literature review was carried out to see if there is evidence of current homeopathic treatment affecting malignant tumours in humans. By current is meant treatment carried out from 1950 - 2008.Results: One systematic review, one chart review and 178 case studies were found of relevance to the study. The general standard of the reviewed cases was above average when compared to the normal limitations found in homeopathic case reports.Conclusion: This literature review shows that evidence of effect of homeopathic treatment of malignant tumours in humans does exist. Further investigation of the anti-cancer effect of homeopathic treatment should be done both in a way that is in line with the underlying theories of homeopathy and also in a meaningful way for patients. Case studies are considered as best evidence when carried out rigorously. However, the case studies need to be further refined in order to share knowledge both inside and outside the homeopathic community.Keywords: Homeopathy, cancer, neoplasm, malignancy, tumour.