| Definitions (1)
Epidemic: An infectious disease that attacks many people
at the same time in the same geographical area.
Endemic: Disease that occurs continuously or in expected cycles
in a population, with a certain number of cases expected for a given
period. e.g. Influenza and the common cold.
Pandemic: A disease effecting the majority of the population of
a large region, e.g. periodontal disease, or one that is epidemic
at the same time in many different parts if the world.
Influenza
There are 3 different strains of influenza virus:
Influenza Strain A |
This virus can still exchange genetic material
with the extremely large number of avian viruses. |
Influenza Strain B
Influenza Strain C |
Entirely human viruses. |
Influenza type A
The exchange of the entire gene segments, called antigenic
shift, happens when a tertiary host e.g.
a pig is infected by both the Influenza A virus and one of the bird
viruses. In some part of China and southeast Asia,
pigs and domestic birds share indoor spaces with humans, creating
the potential for the antigenic drifts.
Antigenic drifts have been observed to occur at irregular time
intervals of at least 10 years. Influenza A infections arise in
Asia and the antigenic shifts have been observed only in this type
of Influenza that has the potential of causing pandemics.
On the surface of the influenza virus there are two different glycoproteins,
hemagglututinin (HA) and neuraminidase (NA). These proteins allow
the virus to attack and infect a susceptible host,
triggering the host immunological responses. Differences in virus
strains are thought to occur due to mutations of HA and NA called
antigenic drifts.
Such mutations occur almost annually in the Southern Hemisphere,
causing a new type of influenza A or B with the potential of starting
an epidemic in the Northern Hemisphere.
Key points so far:
There are extremely large number of avian viruses.
In order for antigenic shift to occur, a tertiary host has to be
infected with both Influenza Type A and an avian flu virus.
Antigenic drifts are a minor mutation change in the protein marker
or antigen that occur from year to year in Southern Hemisphere.
The type of yearly flu for vaccination is predicted from the antigenic
drift.
What about the H5N1 BIRD FLU VIRUS?(2)
H5N1 is principally an avian disease, first seen
in humans in Hong Kong in 1997.
Almost all human cases are thought to be contracted from birds.
Isolated cases of human-to-human transmission in Hong Kong and Vietnam,
but none confirmed.
Birds are susceptible to flu just as humans are.
There are 15 different types of avian flu viruses; H5 and H7 are
amongst the most contagious. H5N1 is usually fatal in birds. A slight
different form of the H5N1 strain has been detected in different
countries, meaning that the H5N1 is not localized in southeast Asia.
Recently the bird strain H5N1 has been found in confirmed in Turkey
and Romania and there is a concern for the health of domestic birds.
Note that in Pakistan several cases of the H7 and H9 strains of
bird flu in poultry were identified, but none of these viruses have
been passed to humans.
Birds can carry many viruses, but good hygiene practices in raising
poultry such as the isolation of domestic birds from wild birds
might reduce the problem. Recall the word susceptibility
when birds are raised in poor conditions, their immune system is
weakened and they become more susceptible to avian flu.
So why all the hype about pandemic?
Bird flu was thought to infect birds only, but in Hong Kong in
1997 the first human cases were seen. Humans catch the disease through
close contact with live infected birds. When a bird is infected,
the virus is shed in their feces, which when dry turns into powder
and can be inhaled.
Symptoms are similar to other types of flu - fever, malaise, sore
throats, coughs and possibly conjunctivitis.
However, one case in Vietnam showed that the virus can affect all
parts of the body. What was not reported in the media was the state
of health of this person. As we know, susceptibility plays a massive
role here.
This could mean that many illnesses, and even deaths, thought to
have been caused by something else, may have been due to the bird
flu virus.
So far, as of November 1, 62 people have died (3) of 122 cases
of human flu in Indonesia, Vietnam, Thailand and Cambodia.
Reality check: SARS killed 800 people worldwide and infected 8,400
since it emerged in November 2002, that is 10%. Susceptibility plaid
a role here too.
Fuel for the hype....(4)
1. One, yes I said only one case in Thailand, with a possible transmission
of the virus where a girl could have caught the disease from her
mother, who later died. I'm sorry for the girl, but again the media
(and the scientists?) "forgot" to inform ushow this mother
and daughter lived. Did they lived with a chicken in their house?
How can we be sure that the girl caught the disease from the mother
and not from the same dead chicken that the mother got it from?
Incidentally, the girl survived the virus.
2. In 2004, two sisters died in Vietnam after possibly
contracting bird flu from their brother who had died from an unidentified
respiratory illness. So, how can an unidentified respiratory
illness all of a sudden become the bird flu? Again it was not mentioned
where these children lived, could they all have independently caught
the avian flu from a household chicken? We do not know this, and
I wonder if UK virology expert Professor John Oxford considered
where the children lives when he said “these cases indicated
the basic virus could be passed between humans, and predicted similar
small clusters of cases would be seen again”. If we knew that
the children caught the virus independently then there would be
no case of avian flu transmission from person to person.
3. Another case in Hong Kong, this time a doctor, possibly
caught the disease from a patient with H5N1 virus. This time however,
we are informed that "it was not conclusively proved".
4. Tamiflu (more later) has been used in Vietnam and one patient
had become partially resistant to it.
Turn off the hype ...(4)
- In Thailand the virus was passed to close relatives and it
has not been stated that the patients had contracted the virus
independently from the same infected bird(s) or if the infection
did actually pass from person to person. Again, we do not know
the state of health of the infected patients, nor the amount of
virus they were infected with. Both of these factors play a crucial
role in establishing the infection.
- In the cases reported, patients were infected with one of the
avian flu viruses, but to have the avian pandemic the flu virus
(Influenza Strain A) and the avian flu virus (Strain H5N1) together
in the same host may mutate and a new virus may be produced. If
another patient with Influenza strain A is infected with the new
Avian virus H5N1 at the same time then the new mutating virus
will become more virulent. In order for a pandemic to be triggered,
the new mutated strain would have to get in close contact with
a patient with an H5N1 virus many times, as each time the mutated
virus will become more virulent. The statistical possibility for
this to happen is very small. In fact it is a very rare event.
Again, the susceptibility of the patient(s) and the amount
of the virus that entered the body will play a role.
- A survivor of the bird flu (5) tells of his experience with
the bird flu: “I'd just got back to Thai Binh, where I'm
originally from, to visit my brothers. They threw a welcoming
dinner where we had our favorite dish, 'tiet canh', which is made
with chopped congealed raw duck blood and herbs“. The interesting
aspect of this story is that only two people got sick one of them
died while the other is telling the story. But what about the
other participants at the banquet? We are not told how many people
feasted on the raw duck blood.
- Some experts are making some sense as the veterinarian Butcher
PhD from the University of Florida's College of Veterinary Medicine
who studied avian flu viruses since 1988. He states, "The
emphasis of all my work has changed to dealing with this madness,"
Butcher said Friday, while briefly back at his office on the UF
campus in Gainesville,"Realistically, avian influenza is
not a threat to people, but everywhere you go, it has turned into
a circus." (6) Confirming my suspicion Dr. Butcher
states: (6)
“There has yet to be a proven case in which one person
is known to have passed the illness on to another”.
"For it to become dangerous to humans, it has to go through
a pretty significant genetic change. If you put this in perspective,
it's not going to happen. For a person to be infected now, it
appears that the exposure level has to be astronomical,"
Butcher said.
- Roche is the only pharmaceutical company that have a successful
vaccine again the bird flu. The patent for Tamiflu is valid until
2012 and despite the prediction of over fifty million deaths,
they do not keep the stock levels to meet the need. However, Roche
is not willing to part with the patent rights and warned others
of the danger of producing a generic version of the vaccine.
During the second week of October the papers reported a surprising
gain in Roche's third quarter, despite a much lower projected
profit reported earlier.
Conventional treatment of the Avian flu in humans:
The conventional treatment would include the use of Tamiflu and
other drugs from the same family such as Relenza (zanamivir). However,
we have seen earlier that to get a “super-virus” capable
to triggering a pandemic, the original H5N1 must have a significant
change in its genetic composition which is likely not to be stable
and mutation may continue. Hence a drug designed for the H5N1 virus
is most likely to be ineffective in treating the super-virus, which
is a completely different virus altogether.
Further, it takes a minimum of 5-6 months for a drug company to
produce an anti-viral vaccine after the start of the pandemic. To
add to the problem, anti-viral medicines do not cure influenza.
They cut down the transmission of the disease and somewhat reduced
the symptoms and complications, including the rate of associated
pneumonias, in those already infected.
Tamiflu does not come without side effects.,Tthe known side effects
include but are not limited to:
Tamiflu side effects |
Flu symptoms (12) |
- Nausea
- Vomiting
- Diarrhea
- Bronchitis
- Stomach pain
- Dizziness
- Headache
- Migraines
- Vertigo
- Respiratory problems
- Muscle pains
|
- fever
- chills/sweats
- cough
- muscle and joint pain
- headache
- fatigue and weakness
- sore throat
- conjunctivitis
|
Further, Tamiflu’s safety and effectiveness have not been
determined in people with chronic heart or lung disease, kidney
failure, or in people with high-risk, underlying medical conditions.
(11)
Other drugs such as Amantadine are now no longer useful. Despite
being a drug for human influenza, Amantadine was given in large
amounts to chickens in China. The results speak for themselves:
“Before 2000 almost no virus was resistant to the drug
Amantadine. By 2004, 15 percent of influenza-A viruses collected
in South Korea, 70 percent in Hong Kong and 74 percent in China
were impervious. During the first six months of 2005, 15 percent
of the influenza-A viruses in the United States were resistant,
up from 2 percent just one year before. " (9)
How about the Avian flu vaccine for humans?
The two studies were published early on-line by the British medical
journal the Lancet because of their important implications for the
coming flu season.
In one paper, international researchers analyzed all the data from
patient studies on the flu vaccine performed worldwide in the past
37 years, and discovered that the vaccine showed at best "a
modest" ability to prevent infection with influenza or its
complications in elderly people. The same vaccine is used globally.
"The runaway 100 percent effectiveness that's touted by proponents
was nowhere to beseen," said Tom Jefferson, lead scientist
for the historical vaccine study. Jefferson is a Rome-based researcher
with the Cochrane Vaccine Fields project, an international consortium
of scientists who systematically review research data.
"There is a wild overestimation of the impact of these vaccines
in the community," he said. "In the case of a pandemic,
we are unsure from the data whether these vaccines would work on
the elderly."
In the second paper, researchers from the U.S. Centers for Disease
Control and Prevention said they had found that influenza viruses,
particularly those from the bird flu strain, had developed high
rates of resistance to the only class of cheap anti-viral medicines
-- drugs that have been used for 30 years, mainly to treat flu once
patients have caught the virus. (9)
What to do for the birds?
The spread of Avian flu is mostly from birds to birds. Infected
birds shed flu virus in their saliva, nasal secretions, and feces.
When susceptible birds are in contact with contaminated excretions
or surfaces contaminated with excretions, they become infected.
Humans get infected when they are in intimate contact with infected
poultry or surfaces contaminated with the virus.
There are two aspects to treating the birds. 1.) There are no rapid,
massive and effective treatment modalities in conventional medicine
for birds. 2.) Far more importance is given to the spread of illness
to humans. Birds are considered better controlled by rapid destruction
of all infected or exposed birds and proper disposal of carcasses.
Sometimes millions of birds are destroyed in this manner. Proper
quarantining and rigorous disinfection of farms are also necessary.
Movement restrictions for live poultry, as in trade are another
important control measure. This is implied both within and between
countries to be effective. Vaccination of chicks is also effective.
For disinfection, heating to 56 degrees C for 3 hours or 60 degrees
C for 30 minutes is best. Common disinfectants, such as formalin
and iodine compounds are also found to be working. The virus survives
at cool temperatures such as contaminated manure for at least three
months. It can survive for up to four days in water, at 22 degrees
C and more than 30 days at 0 degrees C. The virulence of the highly
pathogenic form is so high that a single gram of contaminated manure
can contain enough virus to infect 1 million birds.
Vaccination of poultry in farms is an option that could avoid the
culling of entire flocks of chicken, turkeys, ducks etc, as we have
all witnessed a few years ago in Abbotsford. However, at times there
is some rather disturbing news, for example:
Vaccine may be linked to bird flu cases
The weak strain of avian influenza recently detected at more than
a dozen farms in Ibaraki Prefecture may have been brought about
by artificial contamination, including by the use of vaccines, according
to a farm ministry panel. The use of vaccines to prevent bird flu
is currently banned by law, and the Agriculture, Forestry and Fisheries
Ministry said it would probe the matter further.
According to panel head Hiroshi Kida, a professor at Hokkaido University,
the genetic makeup of the virus found at the Ibaraki farms was strikingly
similar to that of a bird flu virus found in Guatemala and Mexico,
too far for a migrating bird to carry into Japan. It is also different
from other Central American strains of the virus previously found
in other parts of Asia.
This led the panel to suspect that a vaccine developed using the
Central American virus was brought into Japan and used on some birds,
infecting the animals around them, he said.
The ministry has a stock of vaccines to be used in the event of
a massive bird flu outbreak, but has banned its general use because
vaccinated birds will develop the antibody and be indistinguishable
from animals that have really come down with the disease.
The Japan Times: Sept. 3, 2005
... so what are the alternatives?
The following homeopathic remedies (in alphabetical order) are
indicated for (but not limited to) the Avian flu:
Aconite, Arnica, Arsenicum album, Belladonna, Bryonia, Eupatorium,
Euphrasia, Hepar sulph, Gelsemium, Kali bich., Sabadilla, Nux vomica,
Pulsatilla, Phosphorus, Rhus tox and Sulphur.
The prescribed remedy and potency is determined on an individual
basis and under the strict supervision of an experienced and qualified
homeopath. (10)
However prevention is better than cure, so...
For common public (10)
- Avoid direct contact with wild and/or domestic birds
especially in regions where bird flu is reported.
- Avoid drinking contaminated water, particularly when
traveling.
- For those who have back yard poultry farms proper care should
be taken in keeping the coop and surroundings areas clean. Special
attention should be paid to disinfect water and feeding pots thoroughly
and routinely. Seek advice from your veterinarian immediately
if birds become sick and take appropriate action.
For commercial farmers
- In addition to the above, routine large scale disinfection of
the facilities
- Proper disposal of droppings and other waste material
- If culling, dispose of carcasses in a safe manner, like by incineration
- Identify early signs of the bird flu.
For all people
If the Avian flu infection affects anyone, DO NOT PANIC. Go to
your physician or homeopath. Ensure that the treatment does not
cause more harm than the illness.
Poultry meat and eggs are safe to eat provided they are cooked
properly, as the virus is easily destroyed by the heat of cooking.
Wash hands frequently and thoroughly. Soapy water and detergents
are the first line of defense. The Avian flu influenza virus is
very sensitive to detergents that destroy their lipid layer. This
layer is needed to enter cells of animals and therefore removing
this layer, destroys the infectivity. The virus survives well in
water and simple washing may assist the virus to enter into areas
where it is picked up by other birds. Therefore any washing to remove
contamination should always be with detergents (soapy water) or
specific disinfectants.
The biggest danger is bird droppings. The virus likes moist, dirty
conditions, so it is essential to thoroughly disinfect items that
have been in contact with bird droppings -- cages, shoes, clothes
before working with poultry/entry to a place where poultry are kept.
(13)
Learning from history:
The Use of Homeopathic medicines
in the 1918 Influenza Epidemic
There has been much discussion about the merits or otherwise of
Avian Flu anti-viral medicines in the media, but no discussion of
the effectiveness of homeopathy in the treatment of influenza. History
shows us that homeopathy was used by homeopathic physicians in the
USA to treat patients during the 1918-1919 influenza epidemic. From
information recorded by these doctors, homeopathic treatment was
highly successful. In most cases one or two homeopathic medicines
were needed. These are known as the “genus epidemicus”
in an epidemic and become known through the careful observation
of a number of influenza cases. It is difficult to speculate exactly
what homeopathic remedies will work best in a possible Avian flu
epidemic. However there are a number of known ‘flu remedies
that may be useful e.g. Gelsemium, Bryonia, Arnica, Eupatorium perforatum,
Arsenicum etc. In the 1918 epidemic Gelsemium and Bryonia were most
commonly indicated according to the following extracts.
In 1921 W.A. Dewey MD., published a paper in the Journal of
the American Institute of Homeopathy entitled “Homeopathy
in Influenza – A Chorus of Fifty in Harmony”. The following
extracts are from this paper.
• In Philadelphia 26,795 cases of influenza treated by homeopathic
physicians had a mortality rate of 1.05% compared with the conventional
mortality rate of 30%.
• In Connecticut 30 physicians reported 6,602 cases with
55 deaths, (<1%).
• Dr. Roberts in Connecticut also reported 81 cases in the
transport service all treated with homeopathic treatment and all
recovered.
• In a factory in Chicago, Dr. Wieland reported influenza
in 8000 workers with one death. All were treated with Gelsemium.
He reports no aspirin was used and no vaccines.
• Dr Williams in Rhode Island reported no losses from influenza
and a 2.1% loss in those that developed pneumonia. He observed that
doctors using aspirin as the main treatment were having a 60% mortality
in those patients that developed pneumonia.
• Dr. Sappington reports that from 1500 influenza cases recorded
by the Homeopathic Medical Society of the District of Columbia only
15 died. Recoveries in the National Homeopathic Hospital was 100%
• In Ohio, Dr. McCann treated 1000 cases of influenza and
had no losses. He says all credit must be given to homeopathy.
• Raymond Siedel decided to become a homeopathic doctor when
he was a 10 year old delivery boy for a local homeopath. He said
“I saw that people who were taking Aspirin were dying, about
half those who were drinking a lot of whiskey were dying, and those
that received homeopathic remedies were living.”
• It was generally observed by homeopaths in the US at the
time that the use of Aspirin was a major cause of deaths during
the influenza epidemic. Its indirect action came through the fact
that aspirin was taken until prostration resulted and the patient
developed pneumonia.
• In Kentucky Dr. Huff wrote “ I almost invariably
gave (homeopathic medicines) Gelsemium or Bryonia.
I hardly ever lost a case if I got there first, unless the patient
had been sent to a drug store and bought Aspirin, in which event
I was likely to have a case of pneumonia on my hands.”
Reference - courtesy:
Winston, J “The Faces of Homeopathy” Great Auk Publishing
1999
Ms. Angela Hair, NZ representative, WHAC.
In summary
- The possibility that the Avian flu virus will affect humans
is a rare event.
- As of today (Nov 3, 2005) 122 people have been infected. Of
these 62 have died.
- All patients that had an avian flu infection have been in very
close contact with body fluids and wastes of infected birds.
- Although it is a rare possibility, if Influenza virus Strain
A is present at the same time in the same host with an (H5N1),
the virus may develop.
- Conventional vaccination for the human flu in general has been
found a lot less effective than first thought.
- A vaccine for the Avian Flu in humans will not be ready in time.
To create a vaccine for a specific organism, the organism must
be isolated, and by theN people would already be sick. It takes
5-6 months to develop a vaccine.
- To prevent becoming sick with the Avian flu, wash hands properly
and frequently, avoid contaminated water, cook properly eggs and
poultry meats, keep away from contaminated birds and their wastes.
- The real damage from the Avian flu is economical due to the
culling of birds when infected birds are found in an area.
- The stockpiling of drugs like Tamiflu may turnout to be a waste
of public funds as the drug side effects are very similar to the
flu and of course Tamiflu was designed for the Influenza Strain
A and B only, hence it would not be effective in case of Avian
flu in the population.
- The solution: learn from history. Homeopathy has a proven record
of success in case of epidemics and no other form of medicine
can equal such a record.
References
1) Taber's Cyclopedic Medical Dictionary, 1997, 19th Eds, Davis
F.A. COMPANY, Philadelphia
2) http://news.bbc.co.uk/1/hi/world/asia-pacific/4292426.stm
3) http://www.who.int/csr/disease/avian_influenza/country/cases
_table_2005_11_01/en/index.html
4)
http://news.bbc.co.uk/1/hi/health/3422839.stm
5) http://news.bbc.co.uk/1/hi/world/asia-pacific/4226459.stm
6) http://www.gainesville.com/apps/pbcs.dll/article?aid=/200511
01/local/51101021/1078/news
7) http://www.japantimes.co.jp/cgi-bin/getarticle.pl5?nn2005090
3a5.htm
8) http://www.washingtonpost.com/wpdyn/content/article/2005/06/17/ar2005061701214.html
9) Rosenthal e. (2005) studies question effectiveness of flu treatment.
International Hearld Tribune. Wed September 21, 2005.
10) http://www.homeoweb.com/clinic/bird_flu.htm#brd-trt-avlbl
11) http://www.personalhealthzone.com/drug_side_effects/tamiflu.html
12) http://www.tamiflu.com/
13) http://birdfluhype.com/preparedness.html |