Clinical Cases

Case of Cornelia de Langue Syndrome, Mental Retardation

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A useful article about Case of Cornelia de Langue Syndrome, Mental Retardation.Full details about Case of Cornelia de Langue Syndrome, Mental Retardation

Child 14 months old, Master Sunder, was brought to me for delayed development.

The main complaints were of poor weight gain [5.5 kg]. Mental development was very slow and there was no teething / talking.

When I saw the patient for the first time, he looked like a baby monkey. His face, expressions and movements were like that of a small baby monkey. He had plenty of hair all over his body +10. He had bushy eyebrows, long eyelashes, a small nose and thin drawn up legs – features evident of Hirsutism ++.

Life situation:
The child’s mother had a lot of tensions and worries during the pregnancy of this child. The reason being that the mother came from a community where a girl has to be given a heavy dowry, and so the mother of this child wanted a male child. She would always be worried whether she would get a boy or girl. Her sleep was disturbed 3+ and she had severe complaints of acidity 3+ and vomiting 3+ during this period. She would often get up worried at night and would dream that someone was harming her. She felt neglected during pregnancy as there was not much cooperation from her husband.
(In the past, she had gotten an amniocentesis done and went in for an abortion as it was a female child)

Personal history

Appetite           –      Less

Craving            –      Sweets +3

Aversion           –      Nil

Bowel              –      Constipated, passes stool every alternate day.

Feels better after burping; otherwise vomits.

Sweat               –       +++ fan is must, likes air conditioning

Urine                –      Nil

Sleep                –      Gets up with a startle; when patted goes back to sleep.
Thermal modality – Hot

Bath           –       Tepid

Cover         –       Aversion

Weather     –       Comfortable in winter

Past history

Birth weight 2.2 Kg.
P/H/O. Bronchitis, cold, cough, constipation frequently
Cleft palate – operated 3 months back.
Tongue tie – operated

F/H

Mother  –       Cold++                MGF     –      Diabetes

Clinical examination

O/E Flat head, fontanelles open
Hair +10- face, back and all over body, Eyebrows bushy
Hirsutism
Undescended testes ++ bilateral

Diagnosis of this syndrome in the case of Sunder was based on following criteria :

1. Low birth weight
2. Facial features – like that of monkey, small head, hair growth, eye brows bushy etc.
3. Hirsutism
4. Undescended testicles
5. Congenital anomalies – cleft lip and palate
6. Language delay
7. Growth retardation, no teething, etc.
8. Behavioural problems
9. Poor sleep and appetite
10. Mental retardation

Diagnosis:

Congenital Anomalies, Microcephaly. Cornelia De Lange Syndrome.

Prescription : Remedy

1/6/93 Med (30) 3P N SL pill TDS

7/6/93 Playful Active +

Follows objects & movements

Makes an attempt to get up.

Remedy Ct all * 7 days

14/6/93 Recognizes small objects like mango etc.

Activity >>

Remedy Ct all * 7 days

21/6/93 Tooth eruption ++

Remedy Ct all * 7 days

30/6/93 Turns, recognizes +5 Active or rolls++

Wants to go outSmiles

When taken out and brought back, sees home and starts crying Recognizes and shows finger to go out

Extra hair has started falling

Remedy SL PN 3 /week SL 1-1 for 3 months

11/11/93 Improvement +++

Can recognize people / objects, mixes around with everyone.

Can do many things on his own.

Remedy Ct all.

12/12/94 Improvement continues

Hair fall +5

Can recognize more objects

Differentiates taste

Remedy Ct all.

21/4/2001 Patient is alive till last known with considerable improvement in overall performance mentally and physically.

Patient is 9 yrs old, weight of child is 12 kg, and mental age is of four and a half years.

Following improvement is observed in the child :

– Can understand instructions in three languages English, Gujarati and Hindi.
– Understands commands well
– Recognizes voices of family, friends and makes an attempt to speak on phone
– Can hold pencil and scribble
– Makes signals and gestures for whatever he wants
– Likes to keep things in order
– Sensitive and moody in nature
– Loves to mix with older people
– Has developed a good coordination between picture and words.
– Sleeps well
– Loves to listen to music
– Can play with beats and rhythms
– Can play with others
– Desire to travel, to go out, meet people
– Shows way out of the house
– Recognizes good clothes and appreciates with positive gestures
– Loves cold drinks, Mac Donald’s food, drags, insists mother to give such food.
– Whenever there is a pit, understands and moves accordingly.

About the author

Jawahar Shah

Jawahar Shah

Jawahar Shah
Homeopath and the creator of HOMPATH homeopathic software.
8, New Hari Niwas, Dattatray Road, Santacruz (W), Mumbai "“ 54
Tel : 022 "“ 2661 4532, 2661 6561 Fax : 022 "“ 2660 0204
Email : [email protected] Web : www.hompath.com

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