Clinical Cases

Homoeopathic Management of Crest Syndrome: A Case Study

Drs. Vishal Deshpande and Srikanth Jammalamadaka share a case of CREST syndrome in a woman of 30. Consolation aggravates, desires sweets and aggravation walking were among the symptoms leading to the simillimum.


 CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym “CREST” refers to the five main features: calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

Raynaud’s phenomenon is frequently the first manifestation of CREST/lcSSc. Clinically this manifests as a white-blue-red transition in skin color. This phenomenon can lead to digital ulcerations, gangrene, or amputation. Ulceration can predispose to chronic infections of the involved site. This case demonstrates the efficacy of reviewing the totality as per need during course of the treatment.

 Homoeopathic Case Record:

Date:  20/12/2018 Name: Mrs.MP Age/Sex: 30yrs. /Female
Religion: Hindu Education:  10th Standard Occupation: Shopkeeper
Marital status: Married Husband: Paper mill operator Children :- 1 son , 1 daughter
Diet: Non-Veg.

  Chief Complaint:

Location Sensation Modalities Accompaniments
Lower        Extremities

Since 5 years

O- Gradual

P- Slow

–         Pain & Swelling in toes (B/L)

–         Reddish-Brown Discolouration

–         Sticky Offensive Watery Discharges

<Walking +2

< Touch

< Climbing Up Stairs

<Cold application



>Warmth, in Sun

>Covering (wearing Socks )

-Pain in Calves Moving Upwards to knees and Hip



Past History (P/H):Apparently Healthy . No long standing chronic illnesses

Family History (P/H): Husband  – Apparently healthy. Father- Agriculture Mother Agriculture

Personal History (P/H):

  • Appetite: Poor
  • Thirst: Good
  • Stool: Regular, soft stool
  • Urine: Clear
  • Thermal Status: Chilly
  • Sleep: Disturbed


Patient was born in a low socioeconomic joint family. Father and mother do agriculture.  She has 2 younger brothers. All personal relations with family members are good but she is more attached to mother and shares everything with her.

She failed in 10th standard and family quit her studies to do home chores.


She got married at the age of 18 years. Husband works as Operator in papermill. Maintains good relations with husband. started a general store in 2004 and runs it on her own. Inspite of much pain apart from working in shop, she will do tailoring work also.

Anger –When customers hurry her to weigh and pack faster. Feels bad as she can’t walk fast due to her complaint.  Desires to be alone and doesn’t prefer sympathy from others.

On examination (O/E):

General Appearance: Moderately Built, Wheatish, Height: 5’1”

Temp: 98.4o F

Pulse: 76/min Slow Regular

RR: 18/min

BP: 120/70 mm Hg

Weight: 54 kg

Throat: NAD

Systemic examination (S/E):

CNS:  –

CVS: S1S2 Normal

R/S: Clear


Local Examination –B/L toes


* Reddish , Hot to touch,

Tenderness ++


CNS- central Nervous System, CVS- Cardiovascular System, R/S- Respiratory System, P/A- Per Abdomen NAD- Nothing Abnormal Detected

Investigations Ordered: – Doppler Study.

Case Processing:

  • Disease Diagnosis & Miasmatic Understanding with Reasoning:
Disease Diagnosis Reasoning for Disease Diagnosis Reasoning for Miasmatic Understanding
CREST Syndrome -Raynaud’s Phenomenon

-Pain, redness on toes < cold

– < Walking, Touch ++


Gradual Onset

Sensitivity Low

Susceptibility low



Disease Diagnosis: CREST Syndrome

Hahnemannian Classification of

Disease: Chronic individual dynamic Disease3

Dominant Miasm:syco- syphilitic {Refer reasoning column for miasmatic understanding}3

Susceptibility: Low

Sensitivity: low

Potency: 6c

Repetition: Frequent

Totality of Symptoms: Chronic

1] Mind  –          Consolation aggravation

2] Mind –           Industrious

3] Generals –     Food sweet desires

4] Generals –     Walking aggravation

5] Generals –      Touch aggravation

6] Skin ulcers – Discharges offensive

  • Selection of Repertory: Synthesis Repertory
  • Repertorial Sheet:

Repertorial Result:

Chilly Totality & Symptoms Covered Hot Totality & Symptoms Covered

Before treatment :-

Final Selection of Acute Remedy & First Prescription: Considering the thermal status of patient i.e. chilly & the totality covered the final selection of remedy is Silicea 6C

Prescription: Silica 6c BD x WEEKLY

20/12/18 Pain &Discoloration reduced

Swelling remained same

Silicea 6c BD x weekly

Sac lac for one month

11/01/19 Pain &Discoloration>>70%

Swelling reduced slowly

Sac Lac for one month
28/02/19 Pain, discoloration and swelling reduced significantly Sac lac for one month
16/01/20 No pain and swelling Sac lac for one month


For one year patient was not under treatment as she felt better, no complaints were there. But since three months, complaints reappeared as previously, one month after vaccination and also some changes were there in totality, so we decided to review the case.

After treatment:

Case reviewed.

Appetite – good

Thirst –     adequate

Urine –    Normal

Bowel –    Regular

Desires –   Fish +++

Aversion – Not specific

Sleep      – Sound

Thermals – Sensitive to both heat & cold

Life Space Investigation:

Desires solitude and wants to live alone peacefully, Doesn’t want to be consoled. When husband doesn’t lift up a call and children don’t reach home in time, she constantly calls husband or worries why they are late what had happened to them. At present she wants things to be neat, clean and in their  proper place and if not she gets irritated. Becomes very sensitive to the sufferings of others and tries to help if she can.

Totality of Symptoms: Revised

1] Mind – Consolation aggravation

2] Mind – Sympathetic

3] Mind – Industrious

4] Mind- Anxiety others for

5] Mind – Fastidious

6] Generals – food Fish desires

7] Generals – Vaccination, ailments after

Repertorization chart –

Repertorial Result:

Chilly Totality & Symptoms Covered Hot Totality & Symptoms Covered
Sepia 10/6 Natrum mur 11/5
Phosphorus 09/6 Sulphur 06/5
    Lycopodium 06/5

Remedies after repertorization are Phos., Sepia, which are chilly and Nat m., Sulphur, which are hot remedies. Carcinosin is the remedy which can be thermally hot or chilly or sensitive to both. So as per thermals and repertorization Carcinosin was selected as a final remedy.

Before treatment:

Follow up-

23/07/21 Pain started again

Cracks+ Bleeding+

Swelling mild

Carcinosin 1M (1 dose)

Sac lac for one Month

29/08/2021 Pain reduced by 30%, Bleeding+, Cracks+. No new complaint. Physical generals – normal Sac lac for one Month.
26/09/2021 Pain reduced by 60%, Bleeding stopped. Cracks reduced by 50%. No new complaint. Sac lac for one month


After treatment:-

Case was followed up for another six months. In between Carcinosin was repeated once as there was relapse of complaints, but in reduced intensity.

Latest condition of patient as reported:

 Discussion –

In this case Silicea 6c helped in relieving her from all the complaints. She was symptoms free for 1 year. Later on, complaints reappeared; probably covid vaccination may be the triggering factor.  Based on totality, after repertorization Carcinosin 1M was prescribed.

About the author

Vishal Deshpande

Dr. Vishal Deshpande isProfessor & Head of Department of Case Taking & Repertory, JIMS Homoeopathic Medical College & Hospital.

About the author

Srikanth J

Dr Srikanth Jammalamadaka M.D (Hom) is Medical Officer at JIMS Hospital
where he has been working the last 4 years, treating patients of varied clinical presentations from rural backdrop..

1 Comment

  • Allopathy would have nothing to offer in such a case, except perhaps to add side effects with toxic drugs. Thank you Drs. Deshpande and Srikanth.

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