This drug, in common with most of the Apocynaceae, is a cardiac poison, powerfully depressing the heart (in large doses) and causing a weak and irregular pulse. It increases the intestinal secretions and the urine, weakens the sphincters and causes haemorrhoidal engorgement.
The general indications for its administration are dropsies of various sorts, particularly hepatic or cardiac, with an irritable stomach, thirst, though drinking causes distress in the stomach and even vomiting.
Vertigo on suddenly rising after stooping.
Thirst. Stomach irritable; a little food or drink causes distress, nausea and vomiting. Epigastric oppression impedes breathing.
Rectum and Anus
Tenesmus. Protruding piles. Sphincter weak. Soreness in anus.
Loose, undigested, frothy, involuntarily.
Scanty. Often dribbles involuntarily.
Cough short, dry. Respiration short, at times sighing.
Action feeble, intermittent. Sensation of sinking at heart.