Sanguinarinum. C19H17NO4. Trituration. Solution in vinegar.
Clinical
Croup.
Characteristics
*Sanguinarin. is a pearly white substance. In smallest physiological doses it acts as “expectorant, ‘ in large it causes nausea, and still larger vomiting. In repeated doses it lowers the pulse rate (Thomas, quoted *C.D.P.). T. Nichol gives in Hale’s work his experience with a solution of one grain of *Sanguinarin. in two ounces of vinegar in cases of pseudo- membranous croup. (He does not say how much of this he gave or how frequently he repeated: probably the dose was a few drops in water given frequently.) He relates this case: *W. G., 5, had been ill some days. Nichol found him with a hoarse, muffled cough, complete aphonia, pulse 132. Soft palate and fauces covered with pearly, fibrinous exudation, a hissing sound was heard on auscultating larynx. Great dyspnoea. The child stretched back his head and grasped his throat in agony. Features swollen and dark. *Sgn. *acet. was given, and in fifteen hours there was notable improvement. In forty-eight hours the boy was out of danger.