The cutaneous manifestations of this condition are always symptomatic of a grave disease of the blood and may precede or follow the systemic involvement. The lesions have been described as superficial and deep. Among the former are hemorrhages, papules, vesicles, wheals, pigmentations, erythemas, scaling and rarely a moist condition with itching. The deeper lesions are usually present in the form of ulcerations or necrotic areas. Nodules and tumors of widely varying size, shape and color may occur. While these lesions may develop on any part of the body, they are usually found upon the face and extremities.
Pseudoleukemia Cutis – Pseudoleukemia (Hodgkin’s disease) occasionally presents cutaneous symptoms similar to those described above and it is possible that they may be practically the same as the other form.
Etiology, Pathology and Diagnosis – The essential cause of this condition is unknown. The nodules and tumors are situated in the corium and subcutaneous tissue and are composed of crowded accumulations of lymphocytes. Recognition of these eruptions must depend upon the diagnosis of the underlying disease which would indicate that the blood, glands and internal organs should be carefully investigated.
Prognosis and Treatment – While the result is usually fatal, comparative relief has followed the hypodermic use of arsenic. The X-rays should always be tried, if for no other purpose than as a temporary remedy. The external treatment of the lesions is practically that of an eczema for the mild forms and of mycosis fungoides for the more severe types with tumor formation.