Homeopathy Papers

Efficacy of Homoeopathy in Treatment of Sarcoidosis – An Evidence Based Report, Based on 50 cases

Dr. Rajneesh K. Sharma presents a study of the efficacy of homeopathy in treating Sarcoidosis.

Abstract

To ascertain efficacy of Homoeopathy in treatment of sarcoidosis, 50 cases during the period since 2007-2013 were selected for study at Homoeo Cure and Research Institute., Kashipur (INDIA). The efficiency of homoeopathic treatment was miraculously seen in all the cases. Almost all were either cured or much relieved.

Aims and objectives

  • To study scope of Homoeopathy in treatment of ‘Sarcoidosis’ with its miasmatic analysis.
  • To analyze the results of Homoeopathic medicines when prescribed on the basis of Miasms and on totality of symptoms.
  • To prepare an evidence based report on the treatment of Sarcoidosis with Homoeopathy.

Introduction

‘Sarcoidosis’ is a ‘not well understood’ complex multisystem, commonplace inflammatory disease, characterized by the formation of noncaseating granulomas. The granuloma is a battle clashed on a genetically susceptible ground between an unrecognized antigen(s) and a highly organized squad of lymphocytes and macrophages. The lungs are the most commonly involved organs, but no structure of the body is known to be immune to its wrecks.

The cause of sarcoidosis is not known. Though not common, it often leads to permanent failure or disabilities of the organs ultimately leading to the end of vital functions.

‘Sarcoidosis’, like other disease, affects the person as a whole irrespective of the cause. The whole economy of the patient is altered producing the signs of ‘Sarcoidosis’ as well as a characteristic picture of sick individual including mental and physicals specific to his personality. This disease picture specific to that particular patient is always different from that in another one, due to his particular identity proving him to be an ‘Individual’. The totality of symptoms depends upon the Miasms under-running the disease process in that individual.

The Psora being the fundamental miasm plays a maximum role in altering the physiology and rendering the entire imbalance. While in combination with other miasms, it produces the worst stage of the sickness. The syphilis produces destruction of tissues. To combat it, Sycosis and Psora play their vital part. This combination in turn increases the destruction as well as new tissue formation too, producing granulomas and fibromas publishing the complete portrait of Sarcoidosis.

This article examines the current understanding of sarcoidosis in terms of Homoeopathy.

Definition of Sarcoidosis

“Sarcoidosis is a disease characterized by the formation in all of several affected tissues of epithelioid-cell tubercles without caseation though fibrinoid necrosis may be present at the centre of a few, proceeding either to resolution or to conversion into hyaline fibrous tissue”.

Epidemiology of Sarcoidosis

  • Age at presentation 20–40 years
  • More common in females and black people
  • Present throughout the world, but more common in temperate climates

Causes of Sarcoidosis

Possible Causes of Sarcoidosis

MycobacteriaBacteriaFungiVirusesDustsMetals
TuberculousCorynebacterium spp.Cryptococcus spp.CytomegalovirusClayAluminum
Non-tuberculousPropionibacteriumEndemic fungiEpstein-Barr virusPineBeryllium
Cell-wall deficient(L-forms)acnes  Herpes simplex virusPollen Zirconium 
 Tropheryma whippleii Talc 
Mixed

Signs and Symptoms of ‘Sarcoidosis’ with Miasmatic Analysis

  • Up to one-third are asymptomatic
  • Acute presentation (Lofgren’s syndrome) with fever, malaise, arthralgia, erythema nodosum and uveitis
  • Chronic presentation with fever, weight loss, dry cough or SOB
  • Symptoms are usually mild if thoracic disease only

Rarer presentations include-

  • Hypercalcaemia (renal stones, constipation and dehydration)
  • Red eyes
  • Skin rashes
  • Central and peripheral nerve palsies
  • Hypothalamic deficiency
  • Bilateral salivary gland enlargement
  • Cardiomyopathy or arrhythmias
Sign or SymptomFundamental MiasmSecondary/ Associated Miasm
General discomfort, uneasiness, or ill feeling (malaise)PsoraPsora- Syphilis
FeverPsora
Shortness of breathPsoraSycosis
CoughPsoraSycosis, Syphilis
Skin lesionsPsoraSycosis
Skin rashPsora
HeadachePsoraSycosis, Syphilis
Visual changesPsora-Sycosis-Syphilis
Neurological changesSycosis-SyphilisPsora
Enlarged lymph glands (armpit lump)PsoraSycosis
Enlarged liverPsoraSycosis
Enlarged spleenPsoraSycosis
Dry mouthPsora
Fatigue (one of the most common symptoms in children)PsoraSyphilis
Weight loss (one of the most common symptoms in children)Psora-Syphilis
Tearing, decreasedPsoraSycosis, Syphilis
SeizuresPsoraPsora- Syphilis
Nosebleed – symptomPsora- Syphilis
Joint stiffnessPsoraSycosis
Hair lossPsoraSycosis, Syphilis
Eye burning, itching, and dischargePsoraPsora- Syphilis
Abnormal breath sounds (e.g. rales)Psora- SyphilisSycosis

Radiological features of Sarcoidosis

CXR

  • May be normal.
  • Stage 1 – bilateral hilar and mediastinal lymphadenopathy (particularly right paratracheal and aortopulmonary window nodes).
  • Stage 2 – lymphadenopathy and parenchymal disease.
  • Stage 3 – diffuse parenchyma disease only.
  • Stage 4 – pulmonary fibrosis.

Sarcoidosis

Egg shell calcification of both hila

 image002

‘1-2-3 sign’ – Posteroanterior (PA) chest radiograph of a 31-year-old woman with class I sarcoidosis shows right paratracheal (arrowheads) and bilateral hilar (arrows) lymphadenopathy. This pattern of lymphadenopathy is classic for sarcoidosis and is referred to as the 1-2-3 sign or Garland triad.

The parenchymal disease involves reticulonodular shadowing in a perihilar, mid zone distribution. There is bronchovascular and fissural nodularity. Rarely air space consolidation or parenchymal bands may also be present. Fibros is affects the upper zones where the hilar are pulled superiorly and posteriorly. Lymph nodes can demonstrate egg shell calcification.

HRCT

Very good at confirming irregular septal, bronchovascular and fissural nodularity. Traction bronchiectasis, fibrosis and ground glass change may be present. There may also be tracheobronchial stenosis. Also may be seen subdiaphragmatic, cardiac, bone, hepatic and splenic involvement on the same scan.

 image003

CT shows precarinal lymphadenopathy with rim calcification (arrow). This pattern of calcification is referred to as eggshell calcification and is commonly seen with sarcoidosis

image004

A: CT shows ill-defined nodules in a bronchovascular distribution (arrow) in the right upper lobe

B: CT with mediastinal windowing shows right hilar lymphadenopathy (arrow)

C: CT at the level of the inferior pulmonary veins shows left hilar lymphadenopathy (arrow)

D: CT at the level of the lower lobe pulmonary arteries shows subcarinal lymphadenopathy (arrow
)

image005

HRCT. Irregular septal, bronchovascular and fissural nodularity

Radiological Differential diagnosis

  • Lymphoma
  • Infection – TB
  • Lymphangitis carcinomatosis
  • Chronic hypersensitivity pneumonitis

Clinical Staging of Sarcoidosis

Stage 0 A normal chest radiograph
Stage I Lymphadenopathy only
Stage II Lymphadenopathy and lung parenchymal disease
Stage III Parenchymal lung disease only
Stage IV Pulmonary fibrosis

image006

Diagnosis of Sarcoidosis

  • Histological evidence of granulomatous inflammation.
  • The exclusion of the known causes of granulomatous inflammation other than sarcoidosis.
  • Evidence of at least two separate organs involved with the disease.

Examinations and Tests for Sarcoidosis

  • CBC, Chem-7 or Chem-20, ACE levels
  • Chest x-ray to see if the lungs are involved or lymph nodes are enlarged and CT scan
  • Biopsy of  Lymph node, Skin lesion biopsy, lung, Liver, Kidney
  • Bronchoscopy and PFT
  • EKG to see if the heart is involved

Common Complications of Sarcoidosis

  • Diffuse interstitial pulmonary fibrosis and / or Pulmonary hypertension
  • Anterior uveitis and / or Glaucoma and blindness (rare)
  • Cardiac arrhythmias
  • Cranial or peripheral nerve palsies
  • Kidney stones
  • Organ failure, leading to the need for a transplant

Treatment of Sarcoidosis

Treatment of Sarcoidosis

Main Goals of treatment

The treatment depends on

To improve how the organs affected by sarcoidosis workInvolvement of vital organs (e.g., lungs, eyes, heart, or brain)
To relieve symptomsSeverity of symptoms
To shrink the granulomasExtent of affection of the organs.

Sarcoidosis and Homoeopathy

In clinical study carried out at Homoeo Cure and Research Institute, Kashipur, a total 50 cases of Sarcoidosis were considered. The following results were observed in the research.

Master Chart

S. No.12345

Legends

Case no.1319613672140151406314126
Date of Reg.02-09-200722-07-200801-04-200927-04-200914-06-2009Male= MaleF= Female

H= Hindu

Ml= Muslim

SK= Sikh

CH= Christian

SD= Student

HW= House wife

W= Working

NW= Not Working

M= Married

MW= Widow

S= Unmarried

OB= Obese

TH= Thin

MD= Moderate

Pulmo = Pulmonary

Cardio= Cardiological

Nephro= Nephrological

Neuro= Neurological

Arthro= Arthrological

Dermo= Dermatological

Ophth= Ophthalmological

EN= Erythema nodosum

NameGSGKMNKNSAA
SexMFFFF
Age2418412945
OccupationSDSDWHWW
Marital statusSSMMM
CasteSKHHHH
BuiltTHTHOBMDMD
DiagnosisSarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Arthro- ophth)Sarcoidosis (Arthro)Sarcoidosis (Arthro- EN)
MiasmSycosisPseudo-psoraSycosisPsoraPsora
Normal Menses++
Scanty Menses++
Profuse menses
Postmenopausal
Sterility
Family incomeAveragePoorGoodGoodGood
Remedy 1Ars iodTuberculinumPulsatillaRhus ToxRhus Tox
Remedy2IodiumRhus ToxNat murPulsatilla
Remedy3
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultCuredCuredCuredRelievedRelieved
S. No.67891011
Case no.141361416514180142521436916658
Date of Reg.22-06-200910-07-200921-08-200926-10-200911-11-200914-12-2009
NameSPAGSMSBPCUM
SexFMMFMF
Age563834324857
OccupationHWWWNWWHW
Marital statusMMMMMM
CasteHHHMLHH
BuiltOBOBMDMDMDTH
DiagnosisSarcoidosis (Pulmo-arthro)Sarcoidosis (Neuro)Sarcoidosis (Pulmo-Lymphatic)Sarcoidosis (Neuro)Sarcoidosis (Pulmonary)Sarcoidosis (Cardio- Nephro-Pulmonary)
MiasmSycosisPseudo-psoraSycosisPsoraPsoraPseudo-psora
Normal Menses
Scanty Menses+
Profuse menses
Postmenopausal++
Sterility+
Family incomeAverageGoodAveragePoorAverageGood
Remedy 1PulsatillaBeryl metLycopodiumPulsatillaPhosphorusPulsatilla
Remedy2Beryl  metPlumb metBeryl  metThujaPulsatillaDigitalis
Remedy3
Basis of PrescriptionConstitutionalPathologicalPathologicalPathologicalConstitutionalConstitutional
ResultRelievedRelievedRelievedRelievedRelievedRelieved
S. No.1213141516

Legends

Case no.1645816921168681731914476
Date of Reg.24-11-200901-05-201029-03-201003-12-201020-02-2010Male= MaleF= Female

H= Hindu

Ml= Muslim

SK= Sikh

CH= Christian

SD= Student

HW= House wife

W= Working

NW= Not Working

M= Married

MW= Widow

S= Unmarried

OB= Obese

TH= Thin

MD= Moderate

Pulmo = Pulmonary

Cardio= Cardiological

Nephro= Nephrological

Neuro= Neurological

Arthro= Arthrological

Dermo= Dermatological

Ophth= Ophthalmological

EN= Erythema nodosum

NameJSKSAKDAPK
SexFMFFF
Age2242413049
OccupationSDSDWHWW
Marital statusSSMMM
CasteSKHMHH
BuiltTHTHOBMDMD
DiagnosisSarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Arthro- ophth)Sarcoidosis (Arthro)Sarcoidosis (Arthro- EN)
MiasmSycosisPseudo-psoraSycosisPsoraPsora
Normal Menses++
Scanty Menses
Profuse menses++
Postmenopausal
Sterility
Family incomeAveragePoorGoodGoodGood
Remedy 1Ars iodTuberculinumPulsatillaRhus ToxRhus Tox
Remedy2IodiumRhus ToxNat murPulsatilla
Remedy3
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultCuredCuredCuredRelievedRelieved
S. No.171819202122
Case no.149181492215069148011473314847
Date of Reg.21-09-201022-09-201010-12-201024-07-201012-06-201021-08-2010
NameKMMFAPPSVGGB
SexFMMFMF
Age363132544740
OccupationHWWWNWWHW
Marital statusMMMMMM
CasteHMHMLHH
BuiltOBOBMDMDMDTH
DiagnosisSarcoidosis (Pulmo-arthro)Sarcoidosis (Neuro)Sarcoidosis (Pulmo-Lymphatic)Sarcoidosis (Neuro)Sarcoidosis (Pulmonary)Sarcoidosis (Cardio- Nephro-Pulmonary)
MiasmSycosisPseudo-psoraSycosisPsoraPsoraPseudo-psora
Normal Menses
Scanty Menses+
Profuse menses
Postmenopausal++
Sterility
Family incomeAverageGoodAveragePoorAverageGood
Remedy 1PulsatillaBeryl metLycopodiumPulsatillaPhosphorusPulsatilla
Remedy2Beryl  metPlumb metBeryl  metThujaPulsatillaDigitalis
Remedy3
Basis of PrescriptionConstitutionalPathologicalPathologicalPathologicalConstitutionalConstitutional
ResultRelievedRelievedRelievedRelievedRelievedRelieved
S. No.2324252627

Legends

Case no.163591431828-05-20111464314946
Date of Reg.13-06-201109-10-20091631603-05-201002-10-2010Male= MaleF= Female

H= Hindu

Ml= Muslim

SK= Sikh

CH= Christian

SD= Student

HW= House wife

W= Working

NW= Not Working

M= Married

MW= Widow

S= Unmarried

OB= Obese

TH= Thin

MD= Moderate

Pulmo = Pulmonary

Cardio= Cardiological

Nephro= Nephrological

Neuro= Neurological

Arthro= Arthrological

Dermo= Dermatological

Ophth= Ophthalmological

EN= Erythema nodosum

NameAKPNGSRMM
SexMFFFF
Age284252941
OccupationSDSDWHWW
Marital statusMSSMM
CasteSKHHHH
BuiltTHTHOBMDMD
DiagnosisSarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Arthro- ophth)Sarcoidosis (Arthro)Sarcoidosis (Arthro- EN)
MiasmSycosisPseudo-psoraSycosisPsoraPsora
Normal Menses++
Scanty Menses+
Profuse menses
Postmenopausal
Sterility
Family incomeAveragePoorGoodGoodGood
Remedy 1Ars iodTuberculinumPulsatillaRhus ToxRhus Tox
Remedy2IodiumRhus ToxNat murPulsatilla
Remedy3
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultCuredCuredCuredRelievedRelieved
S. No.282930313233
Case no.167841622516434162891643216224
Date of Reg.11-02-201015-04-201105-01-201109-05-201119-07-201115-04-2011
NameKVKBGRBSMAK
SexMMMMMM
Age486234375853
OccupationWWWNWWHW
Marital statusMMMMMM
CasteHHHMLHH
BuiltOBOBMDMDMDTH
DiagnosisSarcoidosis (Pulmo-arthro)Sarcoidosis (Neuro)Sarcoidosis (Pulmo-Lymphatic)Sarcoidosis (Cardio)Sarcoidosis (Pulmonary)Sarcoidosis (Nephro-Pulmonary)
MiasmSycosisPseudo-psoraSycosisPsoraPsoraPseudo-psora
Normal Menses
Scanty Menses
Profuse menses
Postmenopausal
Sterility
Family incomeAverageGoodAveragePoorAverageGood
Remedy 1PulsatillaBeryl metLycopodiumPulsatillaPhosphorusPulsatilla
Remedy2Beryl  metPlumb metBeryl  metThujaPulsatillaDigitalis
Remedy3
Basis of PrescriptionConstitutionalPathologicalPathologicalPathologicalConstitutionalConstitutional
ResultRelievedRelievedRelievedRelievedRelievedRelieved
S. No.3435363738 
Case no.1657116617166821671416757
Date of Reg.18-09-201113-10-201131-10-201120-11-201113-12-2011Male= MaleF= Female

H= Hindu

Ml= Muslim

SK= Sikh

CH= Christian

SD= Student

HW= House wife

W= Working

NW= Not Working

M= Married

MW= Widow

S= Unmarried

OB= Obese

TH= Thin

MD= Moderate

Pulmo = Pulmonary

Cardio= Cardiological

Nephro= Nephrological

Neuro= Neurological

Arthro= Arthrological

Dermo= Dermatological

Ophth= Ophthalmological

EN= Erythema nodosum

NameRSSJRUSUJ
SexMMMFF
Age5147424956
OccupationWWWWHW
Marital statusMMMMM
CasteHHHHH
BuiltTHMDTHTHOB
DiagnosisSarcoidosis(Pulmonary)Sarcoidosis(Ophth)Sarcoidosis(Pulmonary)Sarcoidosis(Pulmonary)Sarcoidosis(Pulmonary- Artho)
MiasmPseudopsora/ SycosisPsora/ SyphilisSycosisPsora/ SyphilisPsora/ sycosis
Normal Menses
Scanty Menses
Profuse menses
Postmenopausal++
Sterility
Family incomeAverageGoodAverageGoodGood
Remedy 1ThujaAur metPulsatillaPulsatillaArgentum nit
Remedy2PulsatillaGelsemiumSulphurLycopodiumCausticum
Remedy3BryoniaColchicumOleander
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultCuredCuredCuredCuredRelieved
S. No.394041424344
Case no.168301693217103173631740817448
Date of Reg.23-09-201217-03-201230-05-201209-09-201223-09-201212-10-2012
NameSRSHSSAGAGNS
SexFMMFFM
Age523246373656
OccupationHWWWHWWW
Marital statusMMMMMM
CasteHMIHHHCH
BuiltMDMDMDTHTHMD
DiagnosisSarcoidosis(ARTHR))Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)
MiasmSycosis/ SyphilisPsoa/ SycosisSycosis/ SyphilisPsoa/ SycosisPsora/ SyphilisPseudo-psora
Normal Menses+
Scanty Menses+
Profuse menses
Postmenopausal+
Sterility
Family incomeAverageAverageGoodGoodGoodGood
Remedy 1TuberculinumLycopodiumMedorrhinumPulsatillaTuberculinumCarcinosin
Remedy2DulcamaraCausticumPulsatillaArnicaSulphurPhosphorus
Remedy3BryoniaCarcinosinPulsatilla
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultCuredCuredRelievedRelievedCuredRelieved
S. No.454647484950
Case no.174501745317460174641767217993
Date of Reg.13-10-201215-10-201217-10-201220-10-201225-12-201205-04-2013
NameJMRNSSPAJBNPSMV
SexMMFFMF
Age414649285527
OccupationWWWWWHW
Marital statusMMMMMM
CasteCHHSKHHH
BuiltMDTHThTHOBTH
DiagnosisSarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis(Arhtro)Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)Sarcoidosis (Pulmonary)
MiasmSycosis/ PsoraPsora/ SycosisSycosis/ PsoraSycosisPsora/ SyphilisSycosis/ Pseudopsora
Normal Menses+
Scanty Menses+
Profuse menses
Postmenopausal+
Sterility
Family incomeGoodPoorGoodAverageGoodAverage
Remedy 1TuberculinumIgnatiaBeryllium metCarcinosinTuberculinumThuja
Remedy2Natrum murAmmonium murRuta gravArgentum nitCicuta verosaPusatilla
Remedy3Arnica
Basis of PrescriptionConstitutionalConstitutionalConstitutionalConstitutionalConstitutionalConstitutional
ResultRelievedRelievedCuredRelievedCuredRelieved

Observations

On analyzing the master chart, the following observations are found-

SexMale

24

Female

26

Age in years0-10

1

11–20

1

21–30

11

31–40

11

41–50

15

51–60

10

61–70

1

OccupationWorking

28

Nonworking

3

Housewife

13

Student

6

Marital statusMarried

44

Single

6

Separated

0

CasteHindu

38

Muslim

6

Christian

2

Sikh

4

BuiltThin

16

Moderate

23

Obese

11

DiagnosisPulmonary

32

Arthropathy

14

Cardio

4

Nephro

3

Ophthalmic

4

Dermo

3

Neuro

5

MiasmPsora

18

Pseudopsora

9

Sycosis

20

Syphilis

6

With MensesNormal Menses

8

Scanty Menses

7

Profuse menses

2

Without MensesPostmenopausal

8

Sterility

1

Family incomeGood

24

Average

19

Poor

7

Remedies with First Remedy Second Remedy      Third Remedy
Frequency of UseArs iod

3

Iodium

3

Bryonia

2

Tuberculinum

7

Rhus tox

3

Colchicum

1

Pulsatilla

15

Natrum mur

4

Oleander

1

Rhus tox

6

Pulsatilla

9

Carcinosin

1

Beryllium met

4

Beryllium met

6

Pulsatilla

1

Lycopodium

4

Plumbum met

3

Arnica

1

Phosphorus

3

Thuja

3

Thuja

2

Digitalis

3

Aur met

1

Gelsemium

1

Argentum nit

1

Sulphur

2

Medorrhinum

1

Lycopodium

1

Carcinosin

2

Causticum

2

Ignatia

1

Dulcamara

1

Arnica

1

Phosphorus

1

Argentum nit

1

Cicuta verosa

1

Ammonium mur

1

Ruta

1

Basis of PrescriptionConstitutional

41

Pathological

9

ResultCured

19

Relieved

31

 

Discussions

Prevalance of Sarcoidosis on basis of Sex

Sarcoidosis was found more prevalent in Male patients (52%) than Females (48%).

image008

Prevalance of Sarcoidosis on basis of Age

Sarcoidosis was found most prevalent in age group 41-50 years (30%) and least in below 20 and above 60 years of ages (all 2%). Age groups 21-30, 31-40 and 51-60 showed almost equal prevalence (20-22 %).

 image010

Prevalance of Sarcoidosis on basis of Occupation

The prevalence of Sarcoidosis was mostly in working patients (56%), house wives (26%), Students (12%) and non-working ones (06%).

image012

 

Prevalance of Sarcoidosis on basis of Marital Status

Sarcoidosis was found more prevalent in married patients (88%) than single ones (12%).

About the author

Rajneesh Kumar Sharma

Rajneesh Kumar Sharma

Dr. Rajneesh Kumar Sharma, M.D. (Hom) practices in Uttaranchal, India. He is CMD of the Homoeo Cure & Research Institute since 1994. He is also the founder of Hindi Vikas Kalyan Samiti, Kashipur JCs, Homoeo Cure & Research Institute.
Dr. Sharma's articles and cases have been published in newsletters and online journals. He has been honored with the Bhartiya Chikitsak Ratna Award 2007, Mother India Award for Udyog Pratibha 2007, Kashipur Gaurav Award 2005, Best International Feature Award 2003 etc. etc. Presently he is practicing at HCRC Pvt. Ltd., Kashipur- Uttaranchal (INDIA).

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