63. Kassab S, Cummings M, Berkovitz S, van Haselen R, Fisher P. Homeopathic Medicines for Adverse effects of Cancer Treatments. Cochrane Database Systematic Review. 2009 Apr 15;(2):CD004845. Cochrane Reviews investigate the effects of interventions for prevention, or treatment of illness, or rehabilitation from illness, in a healthcare setting. Most Cochrane Reviews are based on overviews of randomized controlled trials and other forms of evidence that are deemed to be appropriate. This review was conducted to determine what, if any, evidence (in the opinion of the Cochrane reviewers) exists for the treatment by homeopathy of the effects of conventional cancer therapies. A search through numerous databases revealed 8 controlled trials involved in this area of study, 7 of which were placebo controlled and 1 of which was against an active treatment. In total, the trials covered the outcomes of 664 people who’d been variously suffering from the adverse effects of radiotherapy, chemotherapy or breast cancer treatment. Of the 8, 2 trials exhibited beneficial effects from homeopathy. One of these involved a comparison between the effects of a topical corticosteroid and a homeopathic mother tincture of calendula for the prevention of dermatitis from radiotherapy where the calendula proved to be superior to the drug. The other involved the successful use of a homeopathic complex for stomatatitis caused by chemotherapy.
64. Kayne S. A Pilot Trial to Study the Perceived Effectiveness of Homoeopathic remedies bought Over The Counter (OTC) in British Pharmacies. Journal of the Royal London Homoeopathic Hospital NHS Trust, 1997, January 23-24, 90-94. 1000 questionnaires were sent to 8 UK pharmacies, requesting them to pass the questionnaires to customers. These, questionnaires asked the customers whether or not they found OTC homoeopathic medicines effective for the conditions for which they were purchased. A total of 257 users responded, and the accumulated results showed that 83% of respondents felt better after taking the product.
65. Keil T, Witt CM, Roll S, Vancea W, Webera K, Wegscheiderb K, Willich SN. Homoeopathic versus Conventional Treatment of Children with Eczema: A comparative Cohort Study. Complementary Therapies in Medicine (2008) 16, 15â€”21. This was a prospective, multi-centre, parallel-group, comparative cohort study was conducted in urban and mixed urbanâ€”rural regions of Germany. 118 children suffering from clinically defined eczema seen at 54 homeopathic practices and 64 conventional medical practices were treated for the condition with the respective therapeutic protocols normally used in these clinics, i.e. individualised homeopathic or conventional medical therapy. Treatment occurred over a period of 12 months and the outcomes of the 2 different methods of therapy were assessed at 6 months and 12 months by the children or their parents on the basis of eczema signs and symptoms and the quality of life. Overall, on the basis of clinical symptoms and quality of life, there was little difference in the response rates of both groups to their respective therapies although at 12 months after starting treatment, those children who were treated homeopathically had a greater level of recovery from symptoms than those treated with conventional medicine. No adverse reactions were reported for either group
66. Kim LS, Riedlinger JE, Baldwin CM, Hilli L, Khalsa SV, Messer SA, Waters RF. Treatment of seasonal allergic rhinitis using homeopathic preparation of common allergens in the Southwest Region of the US: A randomized, controlled clinical trial. Annals of Pharmacotherapy. 2005, Apr, 39, 4, 617-24. In this double-blind trial, 34 people diagnosed with moderate to severe seasonal allergic rhinitis were randomly assigned to receive either placebo or a combination of potentised allergens (made from the pollens of trees, grasses or weeds identified as allergens). After the 4 week treatment period using 2 sprays 3 times a day of either the potentised allergen mix or placebo, the trial subjects were assessed on the basis of their allergy specific symptoms using 3 separate questionnaire formats (RQLQ, MOS SF-36 and the WPAI). The potentised allergen mix showed significant positive changes compared to placebo.
67. Klopp R, Niemer W, Weiser M. Microcirculatory effects of a homeopathic preparation in patients with mild vertigo: an intravital microscopic study. Microvasc Res. 2005, 69, 1-2,10-6.The aim of this non-randomized, open study was to test the effectiveness of a homeopathic combination product on variables related to microcirculation in 16 people suffering from vestibular vertigo, compared to a control group of 16 untreated people also suffering from vestibular vertigo. Measurements were carried out in two areas (defined by selecting 60 blood-cell perfused nodal points of arterioles, venules, and capillaries with a mean diameter > or = 40 microns): the cuticulum/subcuticulum of the inside left lower arm and an area 5 mm behind the left earlobe. After 12 weeks of treatment, those people receiving the homeopathic preparation exhibited an increased number of nodal points, increased flow rates of erythrocytes in both arterioles and venules, increased vasomotion, and a slight reduction in hematocrit vs. baseline. None of these changes were observed in the control group. Measurements were also made of partial oxygen pressure and the numbers of cell-wall adhering leucocytes, both of which were significantly increased in the test group compared to the control group. All of these parameters were associated with a reduction in the severity of the vertigo symptoms, both on patient as well as practitioner assessment.
68. Kneusel O, Weber M, Suter A. Arnica montana Gel in Osteoarthritis of the Knee: an open, multicenter clinical trial. Advanced Therapies, 2002, Sep-Oct, 19, 5, 209-18. In this uncontrolled study, 79 people suffering from mild to moderate osteoarthritis of the knee were given a gel containing Arnica and asked to apply it twice daily. They were assessed at 3 and 6 weeks for pain, stiffness and functional ability of the knee. Both assessments showed a significant reduction in pain and stiffness, and a significant improvement in the functional ability of the knee.
69. Kulkarni A, Nagarkar BM, Burde GS. Radiation protection by use of homoeopathic medicines. Proceedings from the 8th Conference of Radiation Oncologists of India, Bombay, December 1986, reported in Hahnemann Homoeopath Sand, 1988 Jan,12, 1, 20-3. 82 patients receiving radiotherapy were randomly assigned to receive placebo, Cobaltum 30C or Causticum 30C as a means of assessing the effects of these against dermatological reactions to the radiotherapy. The homeopathic medicines provided a significant reduction in the degree of radiation reactions when compared to placebo
70. Lamont J., Homoeopathic Treatment of Attention Deficit Hyperactivity Disorder (ADHD). British Homoeopathic Journal, 1997, 86, 196-200. 43 children with ADHD were given either a placebo or an individualised homeopathic medicine, in accordance with a double blind partial crossover dose regime. When the results were compared at the end of the trial, it was found that the homeopathic treatment for ADHD was superior to that using placebo.
71. Launso L, Kimby CK, Henningsen I, Fonnebo V. An exploratory retrospective study of people suffering from hypersensitivity illnesses who attend medical or classical homeopathic treatment. Homeopathy. 2006 Apr;95 (2):73-80. This study reports the results of orthodox medical treatment compared to the homeopathic treatment of various hypersensitivity illnesses in 88 people. 34 of these people were treated using orthodox medical means and 54 using constitutional homeopathy. 24% of those treated medically experienced an improvement in their condition while 57% of those treated with homeopathy experienced similar relief.
72. Ludke R, Weisenauer M. A Meta-analysis of Homeopathic Treatment of Pollinosis with Galphimia glauca. Wiener Medizinische Wochenschrift, 1997, 147, 14, 323-7. In this analysis, 7 randomised double-blind placebo controlled trials and 4 trials without placebo controls were examined to determine the therapeutic benefits of Galphimia glauca in pollinosis. In all studies except for one, Galphimia showed significant benefit over placebo where placebo controls were used, or showed significant clinical benefit where the remedy was not compared to placebo. The recovery rates for Galphimia were comparable with those seen with conventional anti-histamines, but without the same side effects.
73. Maas HPJA. Ulcerative Colitis treated with Homoeopathy British Homoeopathic Journal, July 1993, 82, 179-185. In this retrospective case analysis, 24 people suffering from ulcerative colitis were treated in an Argentinian clinic using constitutional homoeopathy over periods of up to 19 years. Of these 24, 16 patients were assessed as having good outcomes.
74. Manchanda RK, Mehan N, Bahl R, Atey R. Double Blind Placebo Controlled Clinical Trials of Homoeopathic Medicines in Warts and Molluscum contagiosum, CCRH Quarterly Bulletin, 1997, 19, 25-29. This trial was reported in two parts, one to evaluate the efficacy of homoeopathy for warts (remedies included Ruta graveolens, Nitricum acidum, Dulcamara, Causticum and Thuja) the other to evaluate the homoeopathic remedy, Calcarea carbonica, for Molluscum contagiosum. Placebo controlled studies involving a total of 147 subjects using single remedies in 30C potencies three times daily, 200C twice daily and 1M daily, for 15 days, showed that homoeopathy was superior to placebo. Thuja was the most successful of the remedies used for warts.
75. Marian F, Joost K, Saini KD, von Ammon K, Thurneysen A, Busato A. Patient Satisfaction and Side Effects in Primary Care: An observational study comparing Homeopathy and Conventional Medicine. BMC Complement Altern Medorrhinum 2008 Sep 18;8(1):52. This was a study carried out by the Swiss Federal Office of Public Health designed to determine levels of patient satisfaction and the perception of side effects following the use of homeopathic medicine. It was part of a national program designed to evaluate complementary and alternative medicine use in Switzerland. The bulk of the data used in the study came from questionnaires filled in over a specific 4 day period supplied by physicians using conventional medicine, physicians using homeopathic medicine, and from patients who’d filled in questionnaires mailed to them 1 month after treatment. 170 practitioners were involved in the study. A total of 3126 questionnaires were received by the researchers and analysis of these revealed the following. 21% of those treated with homeopathy reported “complete resolution” of the presenting complaint versus 28% of those on conventional therapy and 53% reported “complete satisfaction” with homeopathic treatment versus 40% of those given conventional therapy. The rate of side effects reported by those using homeopathy was less than those given conventional medicine.
76. Maronna U, Weiser M, Klein P. Comparison of the Efficacy and Tolerance of Zeel comp. and Diclofenac for the Oral Treatment of Gonarthrosis. Biological Medicine, 2000, 29, 3, 157-158. Diclofenac, a non-steroidal inflammatory drug, is a commonly prescribed medicine for rheumatic diseases. The effects of this drug were compared to those of Zeel, a homoeopathic complex preparation, with 121 people suffering from gonarthrosis. The trial was designed as a randomised, double-blind, actively controlled parallel study. Assessments for pain, stiffness and functional ability were carried out at 2, 4, 6 and 10 weeks after commencing treatments and by the end of the 10 week period, there were no statistical differences observed in the outcomes of both treatment regimes. The homoeopathic complex product and the drug were equally effective in the management of gonarthrosis.
77. Mathie RT, Farrer S. Outcomes from homeopathic prescribing in dental practice: a prospective, research-targeted, pilot study. Homeopathy. 2007 Apr;96(2):74-81. This paper presented the results of a study into the effectiveness of individualised homeopathic medicines for the management of common dental complaints and the effectiveness of a specific protocol used to collect such data. 14 dentists who routinely practice homeopathy contributed data to the study and data from the observations of and by 726 individual patients were collected. Of the 496 patients who were able to be followed up, 90.1% reported a positive outcome, 1.8% experienced a deterioration of the condition and 7.9% of patients reported no change.
78. Matusiewicz R. The effect of a homoepathic preparation on the clinical condition of patients with corticosteroid dependant bronchial asthma. Biomedical Therapy, 1997, June, 15, 3, 70-74. In this double-blind, randomised, placebo-controlled study, 40 people suffering from corticosteroid- dependant bronchial asthma were given either placebo or a combination homeopathic formula, every 5 to 7 days by subcutaneous injection. Using standard spirometry and granulocyte function to measure the response, researchers found that the combination product provided superior results to placebo.
79. McCutcheon LE. Treatment of anxiety with a homoeopathic remedy Journal of Applied Nutrition, 1996, 48, 1& 2, 2-6. 72 people with above-average levels of anxiety were enrolled in this double-blind, placebo-controlled trial and assigned to either a test or control (placebo) group to assess the relative benefits of a combination homeopathic product designed to relieve anxiety. Using sleep loss as a measure of anxiety, the combination product produced results that were better than those from placebo.
80. Milewska G, Trzebiatowska-Trzeciak O. Homoeopathic Treatment of Alcohol Withdrawal British Homoeopathic Journal, October 1993, 82, 249-251. Alcohol withdrawal and delirium tremens experienced by 30 alcoholics was the focus of this uncontrolled study carried out in a Polish medical clinic. Patients were treated with individualised homeopathy and their progress followed for 2 months. The treatment resulted in a reduced duration of alcohol withdrawal time and delirium tremens in all patients.
81. Mohan GR, et al, Cervical Spondylosis- a Clinical Study, British Homoeopathic Journal, July 1996, 85, 131-133. In this uncontrolled study, 154 people suffering from cervical spondylosis were prescribed either homoeopathic Calcium fluoride, or a remedy selected via repertorisation of their mental and physical general symptoms, and their progress monitored for 1 year. Of those given Calc fluor, clinical improvement was seen in 60% of cases. 48% of those given the remedy arrived at by repertorisation reported clinical improvement.
82. Mohan GR, Anandhi KS. Efficacy of homeopathic drugs in dermatitis of atopic diathesis. Homoeopathic Links, 2003, Winter, 16, 4, 257-260. The authors treated 31 people suffering from either atopic skin and respiratory symptoms, or atopic skin symptoms alone. Both groups were treated with individualised homeopathic therapy over a period of 5 years. During a 6 month assessment period following this treatment, the authors determined that 41% of the group with skin and respiratory symptoms achieved not less than a 76% improvement in symptoms and 58% of the group with skin symptoms alone achieved this outcome.
83. Mohan GR. Efficacy of Homeopathy in Childhood Asthmas. Homeopathic Links, Summer 2007, Vol 20, 104-107. This paper reports of work done in India by homeopath, GR Mohan, looking at the results of the homeopathic treatment of 81 children suffering from clinically defined asthma who had previously been treated unsuccessfully with conventional medicine. This open study involved the use of individually prescribed homeopathic medicines for a period of 2 years as a means of reducing the recurrence of asthma attacks. Results were assessed according the 12 point Modified Borg Scale, a subjective scale used to assess the severity of dyspnoea. At the end of the allotted 2 year period, the results were analysed and it was found that asthma had become controlled in 60.5% of children who’d been treated with homeopathy, and some control was achieved in a further 21%. 12.3% of the group failed to respond to the treatment. The medicines used most frequently in this study were Arsenicum album, Merc solubilis, Hepar sulph, Arsenicum iod, Antimony tart, Pulsatilla and Calcarea carbonica
84. Mojaver YN, Mosavi F, Mazaherinezhad A, Shahrdar A, Manshaee K.. Individualized homeopathic treatment of trigeminal neuralgia: an observational study. Homeopathy. 2007 Apr;96(2):82-6. This uncontrolled study, carried out in the Department of Oral Medicine at Iran’s Rafsanjan University of Medical Sciences, was designed to discover if individually prescribed homeopathic medicines could provide relief from medically diagnosed trigeminal neuralgia. 15 people suffering from the condition were enrolled in the study and after receiving their individual prescriptions they were assessed monthly using a Visual Analogue Scale to gauge the severity of their symptoms. After the results were assessed at 4 months it was found that individualised homeopathic treatment was associated with an average reduction in pain intensity of more than 60%.
85. Müller-Krampe B, Oberbaum M, Dipl-Math PK, Weiser M. Effects of Spascupreel versus hyoscine butylbromide for gastrointestinal cramps in children. Pediatr Int. 2007 Jun;49(3):328-34. In this observational cohort study, 204 children under 12 years of age suffering from gastrointestinal spasms and cramps were given either hyoscine butylbromide, a drug commonly prescribed for these conditions, or Spascupreel, a homeopathic complex. After a 1 week period of treatment, the results from these interventions were assessed by a practitioner reviewing reports from the child’s parent or carer using severity of spasms, pain or cramps, sleep disturbances, eating or drinking difficulties, and the frequency of crying, to measure outcomes according to a 4 point scale. Analysis of the results showed that both medicines provided similar levels of benefit.
86. Muscari-Tomaioli G, Allegri F, Miali E, Pomposelli R, Tubia P, Targhetta A, Castellini M, Bellavite P. Observational Study of Quality of Life in patients with Headache, receiving Homeopathic Treatment. British Homoeopathic Journal, 2001, 90, 189-197. In this study, 53 people suffering from headaches were treated by the individual study authors using constitutionally prescribed homeopathic medicines, completing SF-36 health-related quality of life questionnaires before and 4-6 months after beginning the treatment. More the 60% of the subjects experienced an improvement in the condition.
87. Oberbaum M, Schreiber R, Rosenthal C, Itzchaki M. Homeopathic Treatment in Emergency Medicine, a case series. Homeopathy, 2003, 92, 44-47. In this study, 15 people suffering from orthopaedic trauma were treated in a medical centre with homoeopathy, in addition to standard medical treatment. Treatment was commenced 24 hours after admission. All patients initially received homeopathic Arnica 200C and anxiety was treated with Aconite, Opium, Ignatia or Arsenicum album, all in 200C potency. 24 hours following this treatment, the majority of patients reported a reduction in pain and anxiety. 48 hours after admission, patients were treated with individualised homoeopathic remedies. At discharge, 67% of patients rated the homoeopathic treatment as successful.
88. Oberbaum M, Galoyan N, Lerner-Geva L, et al. The effect of the homeopathic remedies Arnica montana and Bellis perennis on mild postpartum bleeding–a randomized, double-blind, placebo-controlled study: preliminary results. Complement Ther Medorrhinum 2005 Jun, 13, 2, 87-90. Forty women experiencing post-partum bleeding were randomly assigned to receive a mixture of Arnica 30C and Bellis 30C, Arnica 6C and Bellis 6C, or placebo. Mean haemoglobin values were measured at 72 hours post-partum, at which point it was found that those women given homeopathic therapy experienced significantly less change in haemoglobin values than those given placebo.