Clinical Cases

Conn’s Syndrome (Primary Hyperaldosteronism)  A Homeopathic Approach

Conn’s Syndrome (Primary Hyperaldosteronism)  A Homeopathic Approach

Dr.Nikunj Trivedi presents a case of Conn’s Syndrome (Primary Hyperaldosteronism) in a woman of 42. Her anxiety, fear of death, palpitation, nervousness and trembling were clues to the simillimum.

A 42 years old lady, Mrs. S. B.  with tremendous weakness and profound tiredness visited my clinic on 2nd August 2016 with her husband and her parents.She called from Delhi, India to the UK, following diagnosis of a life-threatening illness.Her predominant concern was tiredness, generalised muscle aches and pain, lethargy,chronic disturbed sleep, severe nausea and loss of appetite. She must force herself to eat. She also has episodic headaches with some anxiety precipitated with the diagnosis of hypertension. Her history revealed she had high blood pressure at the birth of her son, diagnosed as gestational hypertension.

She developed blurred vision and haziness around objects. Fine work is veryh stressful. She had a severe leg cramps which made her cry, along with pain in stomach and abdomen.Menses were irregular, black, profuse flow and severe Breast pain in mid-cycle. Unable to bear the touch of clothes.

She was given IBS (Irritable Bowel Syndrome)tablets but that didn’t work due to her abdominal pain and colic and flatulence. Sour eructation before and after food.

She had a severe tremor in both hands and was unable to hold a cup of tea. It could be due to weakness or fear of dropping things.

Emotionally, she very deeply disturbed and constantly crying while giving history, though her husband and her mother were with her. She had a great insecurity about her three children, “What will happen to them, if I die?”

Palpitation at any time, as if her heart is racing with throbbing headache leading her to develop blurred vision. Her GP had also ordered visual field testing.

Her BP readings at home were always random, sometimes very high and sometime normal. MRI and pituitary tests were ordered.

Her weight was 65.2 Kg. Since March 2016 to August 2016, she lost about six kg. weight, suggesting progressive weight loss. When she came to see me, she was 59Kg.

Immediately, the picture of Conn`s Disease strikes my mind, which I compared with NHS notes.

Clinical notes from NHS hospital:

Essential Hypertension BP: 161/89,

  1. Weight:65.2 kg Since March 2016 to August 2016, she lost about six kg.
  2. High Prolactin Level at 1947Mu/L.
  3. Low vitamin D Level at 32nmol/L.
  4. Empty Sella syndrome with Hyperprolactinaemia? MRI was done.

She was prescribed by consultant at hospital:

  1. Anti-Hypertensive
  2. Vitamin-D replacement maintenance
  3. Potassium Tablets…. considering probable diagnosis of CONN`S DISEASE.

But despite of taking all conventional treatment, there was NO Relief.

Homeopathic Evaluation:

Miasm Psoric and Sycotic Fear of death Psychologically very fearful, sensitive, emotional, weeping, Likes sympathy and assurance,

Overgrowth andexcessive secretion from Adrenals




Tubercular Lean, Thin, Dark complexion

Constant Sighing, Crying.



Tubercular diathesis Tendency to lose weight

Severe prostration

Thermal Reaction



Very Chilly With slightest exertion felt exhausted. Low immunity Easily tired and irritated



Low Spirited

Hypersensitive to every changes in life style, Family matters Never well since her last delivery



Bad Effect of



Anti-Hypertensive Treatment H/O:

Gestational Hypertension






 Fine and coarse, both types of tremors Tremors intensified with anxiety with awkwardness.


Family History



No significant history of any major illness in family. NIL


Dark, Mild disposed to lose potassium-Hypokalaemia Ionic Imbalance -Low level of Potassium.

Investigations done by Hospital:

Routine Blood tests: Mild Anaemia Hb: 118g/L (11.8gm%)

Kidney Function: Normal.  FSH, LH, Estradiol normal.

PROLACTIN level: Very high: 1947 mU/L(< 501mU/L)

Vitamin D: 32nmol/L

Neurological examinations: NAD

Important Clinical symptoms Selected:

  1. Constantly Sighing. Oh, God! What happens to me!!! What happens, if I die?
  2. Never well since her last pregnancy or last childbirth due to gestational hypertension.
  3. Fear of Death and deep-seated effect of grief.
  4. Severe cramps everywhere in body-Stomach, muscles, back, fingers.
  5. Great Insecurity about family – What happens, if I die?
  6. Palpitation and anxiety – starts thinking about her complaints.
  7. Anxiety about Family. Herself and others.
  8. Anxiety with sleeplessness. Can`t Bend or lean.
  9. Severe throbbing pulsating headache, with blurred vision. Can`t bend or lean and if she does, then feels breathless.

Homeopathic Management of the case:

Considering her complains, symptoms and investigations in to the Homeopathic totality.

Homeopathic treatment and management of the case was planned as shown:

Stage:1   To relieve her anxiety, fear of death, palpitation, nervousness, trembling, spasms.

*Once her Anxiety gets relieved, the adrenaline and aldosterone secretion will come under control.

Stage:2   To treat her Hypokalemia by finding the exact cause for potassium loss.

*Low level of potassium in the blood serum to prevent muscle weakness, high blood pressure

Stage:3 To control her cramps and tremors

*With the cramps, tremors, she was developing Awkwardness and was dropping the things from hand and unable to hold a cup of tea.

Stage:4 Tomake her gain weight.

By boosting up her immune system-Treating patient holistically.

Stage:5 To control her high level of Prolactin.

While considering her complaint – “Never well since her last child birth”-the prolactin derangement taken from that point alongwith her high blood pressure.

Her Medical Diagnosis of Conn`s Syndrome is a clinical condition where the adrenal glands produce excess aldosterone, resulting in low renin level.

I started her treatment considering all clinical symptoms  with Ignatia, due to  the emotional element and effect of the grief and worry and erratic character of her symptoms,

Ignatia 10 M One dose daily for one week and then one dose every week.

Taking reference from Frans Vermeulen, I found interesting information about Ignatia.

Medicinal activities of Ignatia

Stomachic, febrifuge, anti-choleric, tonic.

Medicinal affinities-  Ignatius bean extracts cause a number of toxic effects, including anxiety, restlessness, enhanced reflexes, dizziness, drowsiness, delicate sense perception, excruciating seizures of the entire body, augmented muscle tension, breathing problems, renal failure as well as death.

Miscellaneous folklore

People in the Philippines customarily used the Ignatius seeds in preparing good luck charms and wore them as amulets to fortify and protect themselves from different ailments. In Malaysia and Java, people extracted the seeds of the Ignatius fruits and utilised them as an arrow poison for their blowguns.

Followed by Tab. Bromocryptinum Mesylatum 3X. One Tablet twice a day for One month, to control her Hyperprolactinemia.

Here are the results

27-06-2016 Prolactin -Before my treatment 1947mU/L (<501)
02-08-2016 She consulted me.
08-02-17 Prolactin-After treatment 235mU/L

This very rare and complicated case of Conn`s disease was treated very successfully without any recurrence to this day Mrs.S.B“s entire family is very happy to see her symptom free and enjoying her normal life.

About the author

Nikunj Trivedi

Dr. Nikunj M Trivedi was born in India - Gujarat and presently lives in England. He graduated Homeopathy with First Rank in University with D.H.M.S (Gold Medallist) and PG-Hom at HCH London.UK. He was honoured as a Fellow by HMA UK and Fellow of British Institute of Homeopathy.
Dr. Trivedi has practiced homeopathy since 1980 with a full-fledged homeopathic hospital in India till 2004. He was affiliated with various Homeopathic College in Gujarat India. With his vast clinical experience in gynaecology and obstetrics, he treats male and female fertility, problems. He invented a technique to open a blocked fallopian tube with intra-uterine use of homeopathic remedies. He also used potentised L-arginine to correct sperm abnormalities. He works on oxidative stress in semen, an underlying cause of sperm DNA damage. He also worked on eosinophilia, considering the real obstacles to cure in many clinical conditions. Dr. Trivedi migrated to the UK in 2004 and established a clinical practice in Leicester. Presently he serves as Chairman- UK HMA. His publications related to Infertility are:
1. Repertory of Infertility.
2. Materia Medica of Sexual Disorders
3. Sperm Disorders and Homeopathy.
4. Mind at Menopause.


  • Thanks for sharing this case, it is very interesting to me as a student to see your precise methodology. The positive outcome for this patient is very inspiring. Thank you.

    • Thanks for your appreciation. As a medically qualified Homeopath, I always treat my patients on their Clinical picture with necessary investigations along with Homeopathic treatment….it’s TRIVEDI’s protocol. Please, visit You will be able to find some Evidence based cases. Many thanks,Dr.Nikunj Trivedi

  • My hyperaldosteronism is symptomless other than high blood pressure, around the 250/150 with low heart rate between 59 and 65. My temp is low, maybe indicating uneractive thyroid also. Hysterectomy 10 years ago. age 63. Feel great, medications for BP all didnt agree so i have stopped all. Eat low salt diet paleo style food. Take mg and fish oil supp. and aged garlic. Have tried Ars Alb. I have no fear of death, happy to enjoy each day. Due for the salt loading test soon to confirm the western diagnosis but i am a homeopath and herbalist for animals so keen to cure naturally.

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